My child has gone from monthly rifaximin to continuous rifaximin over several months and we didn’t see much improvement. We added VNS 5 minutes per day and it wasn’t until we added a second 5 mins of VNS that we saw significant gains. Why is this?

It’s difficult to always explain in particular why some children need more inflammation suppression than others. Each of these steps has an additive effect in reducing inflammation more. In this case, it finally took two doses of VNS per day to make a difference. Sometimes I’ve had to add inulin to twice daily rifaximin or change rifaximin to 3 times a day before significant recovery occurs.