After Inulin Failure I moved on to Rifaximin. Now I am worried that one day Rifaximin might stop working. Is there such a thing as Rifaximin Failure?

Unlike other common antibiotics, rifaximin does not lower intestinal bacterial biodiversity, and the development of long-term bacterial resistance to rifaximin is rare even with continuous, daily dosing over a year or more.  Although bacterial resistance to rifaximin occurs very rarely, the resistance quickly disappears after discontinuing rifaximin for only a few weeks. The rifaximin can then be restarted with the same positive effect.nn