After a few months of Monthly Rifaximin I am still not seeing any changes. What should I do?
Even with monthly rifaximin, some patients still will not show evidence of recovery, and this is because they are relapsing even before the next course of rifaximin has begun. If a patient is not showing any improvement after three months of rifaximin, I start these patients on non-stop, twice daily, continuous rifaximin along with five minutes of daily vagus nerve stimulation. nThe children are relapsing rapidly because of slow intestinal motility, often from autonomic nervous system damage. I believe that the addition of vagus nerve stimulation in the patient will help insure their intestinal motility can improve to the degree that continuous rifaximin can ultimately be discontinued.